STAT6 antibody
GTX82421
Overview
- SupplierGeneTex
- Product NameSTAT6 antibody
- Delivery Days Customer10
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- HostChicken
- IsotypeIgY
- Scientific DescriptionCarries out a dual function: signal transduction and activation of transcription. Involved in interleukin-4 signalling. The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors. STAT family members are phosphorylated by the receptor associated kinases. and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L). which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells. expression of cell surface markers. and class switch of immunoglobulins.
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203