STAT6 antibody

GeneTex

STAT6 antibody

9

WB: 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

Unconjugated

STAT6

signal transducer and activator of transcription 6

D12S1644; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; STAT, interleukin4-induced; STAT6B; STAT6C; transcription factor IL-4 STAT

Chicken

IgY

Signal transducer and activator of transcription 6

Carries out a dual function: signal transduction and activation of transcription. Involved in interleukin-4 signalling. The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors. STAT family members are phosphorylated by the receptor associated kinases. and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L). which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells. expression of cell surface markers. and class switch of immunoglobulins.

-20°C or -80°C,2°C to 8°C

12352203