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Stemazole [317337-07-8]

Stemazole [317337-07-8]

T28866
TargetMol Chemicals
Estimated Purity98.17%
Product group Chemicals
Molecular Weight267.33
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Stemazole [317337-07-8]
  • Delivery Days Customer
    4
  • Certification
    Research Use Only
  • Chemical Name
    Stemazole
  • Estimated Purity
    98.17%
  • Molecular Formula
    C9H9N5OS2
  • Molecular Weight
    267.33
  • Scientific Description
    Stemazole is a novel small molecule human stem/progenitor cell proliferation activator that promotes the survival of human embryonic stem cells and maintains stemness, and promotes the survival of oligodendrocyte precursor cells in vitro. Stemazole significantly increased cell survival and clone formation in a dose-dependent manner, reduced apoptosis, and promoted recovery of motor dysfunction and myelin repair. Stemazole can be used as a therapeutic agent in demyelinating disorders, promoting OPC survival in vitro and regeneration in vivo.
  • Shelf life instruction
    3 years
  • SMILES
    S=C1OC(C2=CC=C(NC(NN)=S)C=C2)=NN1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Zhu Y, Chen M, Zhang Y, et al. Stemazole Promotes Oligodendrocyte Precursor Cell Survival In Vitro and Remyelination In Vivo. Int J Mol Sci. 2022,23(18). doi: 10.3390/ijms231810756
    Read this paper