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STF-62247

M8189
AbMole BioScience
CAS Number315702-99-9
Product group Chemicals
Molecular Weight267.35
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    STF-62247
  • Delivery Days Customer
    9
  • CAS Number
    315702-99-9
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C15H13N3S
  • Molecular Weight
    267.35
  • Scientific Description
    Stf-62247 is an autophagy inducer with selective cytotoxicity against VHL-deficient renal cell carcinoma, with IC50 of 0.625 uM and 16 uM in RCC4 and RCC4/VHL cells, respectively. Stf-62247 can trigger ADCD in glioblastoma cell lines (LN-229, MZ-54, GOS-3 and U343) by inducing dephosphorylation and inactivation of mTORC1.
  • SMILES
    CC1=CC(=CC=C1)NC2=NC(=CS2)C3=CC=NC=C3
  • UNSPSC
    12352200