Immunohistochemistry of paraffin-embedded human lymph node tissue using CSB-PA022829LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lymph node tissue using CSB-PA022829LA01HU at dilution of 1:100
STIM1 Antibody
CSB-PA022829LA01HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetSTIM1
Overview
- SupplierCusabio
- Product NameSTIM1 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID6786
- Target nameSTIM1
- Target descriptionstromal interaction molecule 1
- Target synonymsD11S4896E; GOK; IMD10; STRMK; stromal interaction molecule 1; TAM; TAM1
- HostRabbit
- IsotypeIgG
- Protein IDQ13586
- Protein NameStromal interaction molecule 1
- Scientific DescriptionPlays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores (PubMed:15866891, PubMed:16005298, PubMed:16208375, PubMed:16537481, PubMed:16733527, PubMed:16766533, PubMed:16807233, PubMed:18854159, PubMed:19249086, PubMed:22464749, PubMed:24069340, PubMed:24351972, PubMed:24591628, PubMed:26322679, PubMed:25326555). Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit ORAI1 (PubMed:16208375, PubMed:16537481). Involved in enamel formation (PubMed:24621671). Activated following interaction with TMEM110/STIMATE, leading to promote STIM1 conformational switch (PubMed:26322679).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203