STING agonist-24

Biorbyt

STING agonist-24

10

Research Use Only

98.00%

C34H37N13O5

707.74

STING agonist-24 (CF504), a non-nucleotide small-molecule STING agonist, activates STING, leading to increased phosphorylation of STING, TBK1, and IRF3. It elevates levels of IFN-beta, IL-6, CXCL-10, TNF-alpha, ISG-15, and CCL-5 in tumor cells, demonstrating activity against SARS-CoV series strains [1].

C(/C=C/CN1C=2C(N=C1NC(=O)C=3N(CC)N=C(C)C3)=CC(C(N)=O)=CN2)N4C=5C(N=C4NC(=O)C=6N(CC)N=C(C)C6)=CC(C(N)=O)=CC5OC

-20°C

12352200