STING agonist-25

Biorbyt

STING agonist-25

10

Research Use Only

98.00%

C36H41N13O6

751.79

STING agonist-23 (CF505) is a non-nucleotide, small-molecule compound that stimulates STING, enhancing the phosphorylation of STING, TBK1, and IRF3. It elevates the production of IFN-beta, IL-6, CXCL-10, TNF-alpha, ISG-15, and CCL-5 in tumor cells and demonstrates efficacy against SARS-CoV strains [1].

C(/C=C/CN1C=2C(N=C1NC(=O)C=3N(CC)N=C(C)C3)=CC(C(N)=O)=CN2)N4C=5C(N=C4NC(=O)C=6N(CC)N=C(C)C6)=CC(C(N)=O)=CC5OCCCO

-20°C

12352200