Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using STK40 Polyclonal Antibody at dilution 1:40
STK40 Polyclonal Antibody
E-AB-14693
Product group Antibodies
Overview
- SupplierElabscience
- Product NameSTK40 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA IHC
- CertificationResearch Use Only
- Concentration0.3mg/ml
- Scientific DescriptionSTK40 (Serine/threonine-protein kinase 40), also known as Sugen kinase 495, is a 435 amino acid protein kinase that may be a negative regulator of NFkappaB and p53-mediated gene expression. Localized to both the cytoplasm and the nucleus, STK40 is ubiquitously expressed. STK40 has a central serine/threonine protein kinase domain and is homologous to TRB-3, a protein that regulates activation of MAP kinases and inhibits NFkappaB-mediated gene transcription. Similarly, overexpression of STK40 inhibits NFkappaB activation triggered by TNF and also inhibits p53-mediated transcription. There are four named isoforms of STK40 that are produced as a result of alternative splicing.
- UNSPSC12352203





