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STK40 Polyclonal Antibody

RD77802A
Reddot Biotech
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
TargetSTK40
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    STK40 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.3 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID83931
  • Target name
    STK40
  • Target description
    serine/threonine kinase 40
  • Target synonyms
    Ser/Thr-like kinase; serine/threonine-protein kinase 40; SgK495; SHIK; SINK-homologous serine/threonine-protein kinase; sugen kinase 495
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    STK40 (Serine/threonine-protein kinase 40), also known as Sugen kinase 495, is a 435 amino acid protein kinase that may be a negative regulator of NFkappaB and p53-mediated gene expression. Localized to both the cytoplasm and the nucleus, STK40 is ubiquitously expressed. STK40 has a central serine/threonine protein kinase domain and is homologous to TRB-3, a protein that regulates activation of MAP kinases and inhibits NFkappaB-mediated gene transcription. Similarly, overexpression of STK40 inhibits NFkappaB activation triggered by TNF and also inhibits p53-mediated transcription. There are four named isoforms of STK40 that are produced as a result of alternative splicing.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203

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