Chemical Structure
Streptochlorin [120191-51-7]
AG-CN2-0141
Overview
- SupplierAdipoGen Life Sciences
- Product NameStreptochlorin
- Delivery Days Customer10
- CAS Number120191-51-7
- CertificationResearch Use Only
- Estimated Purity>95%
- Hazard InformationWarning
- Molecular FormulaC11H7ClN2O
- Molecular Weight218.6
- Scientific DescriptionAntibiotic [1]. TNF-alpha-induced NF-kappaB activation inhibitor [1]. Antiangiogenic [1]. Apoptosis inducer [2-4]. Anticancer compound. Selective cytotoxic against several cancer cell lines [2-4]. Tyrosinase inhibitor [5]. - Chemical. CAS: 120191-51-7. Formula: C11H7ClN2O. MW: 218.6. Isolated from Streptomyces roseolilacinus. Antibiotic. TNF-alpha-induced NF-kappaB activation inhibitor. Antiangiogenic. Apoptosis inducer. Anticancer compound. Selective cytotoxic against several cancer cell lines. Tyrosinase inhibitor.
- SMILESClC1=C(OC=N1)C1=CNC2=CC=CC=C12
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
References
- Streptochlorin, a marine natural product, inhibits NF-kappaB activation and suppresses angiogenesis in vitro: I. K. Choi, et al.; J. Microbiol. Biotechnol. 17, 1338 (2007)
- Isolation and structure determination of streptochlorin, an antiproliferative agent from a marine-derived Streptomyces sp. 04DH110: H. J. Shin, et al.; J. Microbiol. Biotechnol. 17, 1403 (2007)
- Streptochlorin isolated from Streptomyces sp. induces apoptosis in human hepatocarcinoma cells through a reactive oxygen species-mediated mitochondrial pathway: D. Y. Shin, et al.; J. Microbiol. Biotechnol. 18, 1862 (2008)
- Induction of apoptosis by streptochlorin isolated from Streptomyces sp. in human leukemic U937 cells: C. Park, et al.; Toxicol. In Vitro 22, 1573 (2008)
- Physicochemical characters of a tyrosinase inhibitor produced by Streptomyces roseolilacinus NBRC 12815: T. Nakashima, et al.; Biol. Pharm. Bull. 32, 832 (2009)