Streptozotocin [18883-66-4]

AdipoGen Life Sciences

Streptozotocin

10

18883-66-4

Research Use Only

>98%

Danger

C8H15N3O7

265.2

Antibiotic [1]. Diabetogenic. Diabetes inducer. Induces diabetes mellitus in animal models through its toxic effects on pancreatic beta-cells [2, 5, 13, 14]. Mutagenic [3, 10]. Potent alkylating agent. Potent DNA methylating agent [4, 10]. Nitric oxide (NO) donor. Vasorelaxant [6]. Cytotoxic to cells that express GLUT2 glucose transporter [7]. O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase (O-GlcNAcase) inhibitor [8]. Genotoxic. Induces DNA damage. Produces DNA strand breaks [9, 10]. Cell death inducer [15]. Antineoplastic. Anti-cancer agent used in chemotherapy [10, 11]. Induces cell cylce arrest at G2 [12]. - Chemical. CAS: 18883-66-4. Formula: C8H15N3O7. MW: 265.2. Antibiotic. Diabetogenic. Diabetes inducer. Induces diabetes mellitus in animal models through its toxic effects on pancreatic beta-cells. Mutagenic. Potent alkylating agent. Potent DNA methylating agent. Nitric oxide (NO) donor. Vasorelaxant. Cytotoxic to cells that express GLUT2 glucose transporter. O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase (O-GlcNAcase) inhibitor. Genotoxic. Induces DNA damage. Produces DNA strand breaks. Cell death inducer. Antineoplastic. Anti-cancer agent used in chemotherapy. Induces cell cylce arrest at G2.

CN(N=O)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O

-20°C,2°C to 8°C

12352200