SU4312

MedChem Express

SU4312 [5812-07-7]

5

5812-07-7

99.76

C17H16N2O

264.32

SU4312 is the racemate of (Z)-SU4312 and (E)-SU4312. (Z)-SU4312 inhibits PDGFR and FLK-1 with IC 50 s of 19.4 and 0.8 microM, respectively. (E)-SU4312 inhibits PDGFR, FLK-1, EGFR, HER-2, and IGF-1R with IC 50 s of 24.2, 5.2, 18.5, 16.9 and 10.0 microM, respectively [1] .

O=C1NC2=C(C=CC=C2)/C1=C/C3=CC=C(N(C)C)C=C3

-20°C,2°C to 8°C

12352200