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Suberoyl bis-hydroxamic acid

HY-W009776
MedChem Express
CAS Number38937-66-5
Product group Chemicals
Estimated Purity98.0
Molecular Weight204.22
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Suberoyl bis-hydroxamic acid [38937-66-5]
  • Delivery Days Customer
    9
  • CAS Number
    38937-66-5
  • Certification
    Research Use Only
  • Estimated Purity
    98.0
  • Molecular Formula
    C8H16N2O4
  • Molecular Weight
    204.22
  • Scientific Description
    Suberoyl bis-hydroxamic acid (Suberohydroxamic acid; SBHA) is a competitive and cell-permeable HDAC1 and HDAC3 inhibitor with ID50 values of 0.25 microM and 0.30 microM, respectively[1].Suberoyl bis-hydroxamic acid renders MM cells susceptible to apoptosis and facilitates the mitochondrial apoptotic pathways[2].Suberoyl bis-hydroxamic acid can be used for the study of medullary thyroid carcinoma (MTC)[3].
  • SMILES
    O=C(NO)CCCCCCC(NO)=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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