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Substance P antibody [NC1/34]

Research Use Only
GTX38990
GeneTex
ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityAmphibian, Avian, Bovine, Chicken, Camel, Fish, Guinea Pig, Human, Insect, Mammals, Mouse, Porcine, Rabbit, Rat, Sheep, Zebra Fish, Other Species
TargetTAC1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Substance P antibody [NC1/34]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody recognizes the COOH terminal end of substance P.
  • Application Supplier Note
    IHC-P: 1/100-1/200. IHC-Fr: 1/100-1/200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    NC1/34
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID6863
  • Target name
    TAC1
  • Target description
    tachykinin precursor 1
  • Target synonyms
    Hs.2563; neurokinin 1; neurokinin 2; neurokinin A; neurokinin alpha; neuromedin L; neuropeptide gamma; neuropeptide K; NK2; NKNA; NPK; PPT; preprotachykinin; protachykinin; protachykinin-1; substance K; substance P; TAC2; tachykinin 2; tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)
  • Host
    Rat
  • Isotype
    IgG2a
  • Protein IDP20366
  • Protein Name
    Protachykinin-1
  • Scientific Description
    This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]
  • Reactivity
    Amphibian, Avian, Bovine, Chicken, Camel, Fish, Guinea Pig, Human, Insect, Mammals, Mouse, Porcine, Rabbit, Rat, Sheep, Zebra Fish, Other Species
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Covering the proximal nerve stump with chondroitin sulfate proteoglycans prevents traumatic painful neuroma formation by blocking axon regeneration after neurotomy in Sprague Dawley rats. He FL et al., 2020 May 29, J Neurosurg
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  • Neural Regeneration/Remodeling in Engineered Coronal Pulp Tissue in the Rat Molar. Sone PP et al., 2020 Jul, J Endod
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  • Angiotensin-converting enzyme inhibitor works as a scar formation inhibitor by down-regulating Smad and TGF-beta-activated kinase 1 (TAK1) pathways in mice. Tan WQ et al., 2018 Nov, Br J Pharmacol
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