SUCLG1 antibody
![Research Use Only](static/images/certificates/ruo.jpg)
GTX109215
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSUCLG1
Overview
- SupplierGeneTex
- Product NameSUCLG1 antibody
- Delivery Days Customer9
- Antibody SpecificityKnockdown/Knockout validation was supported by references (PMID:26990993)
- Application Supplier NoteWB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.48 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID8802
- Target nameSUCLG1
- Target descriptionsuccinate-CoA ligase GDP/ADP-forming subunit alpha
- Target synonymsGALPHA; MTDPS9; SCS-alpha; succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; succinate-CoA ligase alpha subunit; succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial; succinyl-CoA synthetase subunit alpha; SUCLA1
- HostRabbit
- IsotypeIgG
- Protein IDP53597
- Protein NameSuccinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
- Scientific DescriptionThis gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Resources for the Comprehensive Discovery of Functional RNA Elements. Sundararaman B et al., 2016 Mar 17, Mol CellRead more
- Screen for abnormal mitochondrial phenotypes in mouse embryonic stem cells identifies a model for succinyl-CoA ligase deficiency and mtDNA depletion. Donti TR et al., 2014 Feb, Dis Model MechRead more