Sulfamerazine (sodium salt) [127-58-2]

MedChem Express

Sulfamerazine (sodium salt) [127-58-2]

10

127-58-2

Research Use Only

C11H11N4NaO2S

286.29

Sulfamerazine Sodium is a sulfonamide antibacterial. Target: Antibacterial Sulfamerazine, the monomethyl derivative of sulfadiazine, is 2-sulfanilamido-4-methylpyrimidine. Sulfamerazine is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthetase (dihydrofolate synthetase). Sulfamerazine is bacteriostatic in nature. Inhibition of dihydrofolic acid synthesis decreases the synthesis of bacterial nucleotides and DNA [1].

O=S([N-]C1=NC=CC(C)=N1)(C2=CC=C(N)C=C2)=O.[Na+]

12352200