Sulfopin

MedChem Express

Sulfopin [2451481-08-4]

10

2451481-08-4

Research Use Only

99.69

C11H20ClNO3S

281.805

Sulfopin (PIN1-3) is a highly selective covalent inhibitor of Pin1 with an apparent K i of 17 nM. Sulfopin blocks Myc-driven tumors in vivo. The peptidyl-prolyl isomerase, Pin1, is exploited in cancer to activate oncogenes and inactivate tumor suppressors [1] .

O=C(N(CC(C)(C)C)C(CC1)CS1(=O)=O)CCl

-20°C,2°C to 8°C

12352200