Sulfoxaflor [946578-00-3]

MedChem Express

Sulfoxaflor [946578-00-3]

10

946578-00-3

Research Use Only

99.92

C10H10F3N3OS

277.27

Sulfoxaflor is an orally active full agonist of insect nicotinic acetylcholine receptors (nAChRs), targeting the alpha-bungarotoxin-insensitive nAChR1 and nAChR2 subtypes. Sulfoxaflor binding to nACh is not inhibited by d-Tubocurarine (HY-125901), but is partially inhibited by Mecamylamine (HY-B1395A). Sulfoxaflor induces inward currents by activating nAChRs, leading to insect neurotoxicity. Sulfoxaflor can be used in the research of agricultural pest control, pesticide toxicology, insect neural receptor pharmacology, etc[1][2].

CC(C1=CC=C(C(F)(F)F)N=C1)S(=NC#N)(C)=O

-20°C,2°C to 8°C

12352200