Sulfoxaflor-d3

MedChem Express

Sulfoxaflor-d3

999

Research Use Only

C10H7D3F3N3OS

280.28

Sulfoxaflor-d3 is the deuterium labeled Sulfoxaflor (HY-118504). Sulfoxaflor is an orally active full agonist of insect nicotinic acetylcholine receptors (nAChRs), targeting the alpha-bungarotoxin-insensitive nAChR1 and nAChR2 subtypes. Sulfoxaflor binding to nACh is not inhibited by d-Tubocurarine (HY-125901), but is partially inhibited by Mecamylamine (HY-B1395A). Sulfoxaflor induces inward currents by activating nAChRs, leading to insect neurotoxicity. Sulfoxaflor can be used in the research of agricultural pest control, pesticide toxicology, insect neural receptor pharmacology, etc[1][2].

O=S(C(C1=CC=C(N=C1)C(F)(F)F)C([2H])([2H])[2H])(C)=NC#N

12352200