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ICC/IF analysis of C-33A cells using GTX00701 SUMO1 antibody [4D12]. SUMO-1 colocalizes with SUMO2/3. Left : anti-SUMO-1 antibody (4D12) Middle : anti-SUMO2/3 antibody (3H12) Right : Merged image Dilution : 10 microg/ml
ICC/IF analysis of C-33A cells using GTX00701 SUMO1 antibody [4D12]. SUMO-1 colocalizes with SUMO2/3. Left : anti-SUMO-1 antibody (4D12) Middle : anti-SUMO2/3 antibody (3H12) Right : Merged image Dilution : 10 microg/ml
ICC/IF analysis of C-33A cells using GTX00701 SUMO1 antibody [4D12]. SUMO-1 colocalizes with SUMO2/3. Left : anti-SUMO-1 antibody (4D12) Middle : anti-SUMO2/3 antibody (3H12) Right : Merged image Dilution : 10 microg/ml

SUMO1 antibody [4D12]

GTX00701
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
TargetSUMO1
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Overview

  • Supplier
    GeneTex
  • Product Name
    SUMO1 antibody [4D12]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000. ICC/IF: 1:100. IHC-Fr: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    4D12
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7341
  • Target name
    SUMO1
  • Target description
    small ubiquitin like modifier 1
  • Target synonyms
    DAP1, GMP1, OFC10, PIC1, SENP2, SMT3, SMT3C, SMT3H3, UBL1, small ubiquitin-related modifier 1, GAP modifying protein 1, SMT3 homolog 3, SMT3 suppressor of mif two 3 homolog 1, sentrin, ubiquitin-homology domain protein PIC1, ubiquitin-like protein SMT3C, ubiquitin-like protein UBL1
  • Host
    Rat
  • Isotype
    IgG2a
  • Protein IDP63165
  • Protein Name
    Small ubiquitin-related modifier 1
  • Scientific Description
    This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Uchimura Y, Ichimura T, Uwada J, et al. Involvement of SUMO modification in MBD1- and MCAF1-mediated heterochromatin formation. J Biol Chem. 2006,281(32):23180-90.
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  • Saitoh N, Uchimura Y, Tachibana T, et al. In situ SUMOylation analysis reveals a modulatory role of RanBP2 in the nuclear rim and PML bodies. Exp Cell Res. 2006,312(8):1418-30.
    Read this paper