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Supinoxin [888478-45-3]

HY-123611
MedChem Express
CAS Number888478-45-3
Product group Chemicals
Estimated Purity99.67
Molecular Weight441.46
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Supinoxin [888478-45-3]
  • Delivery Days Customer
    10
  • CAS Number
    888478-45-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.67
  • Molecular Formula
    C22H24FN5O4
  • Molecular Weight
    441.46
  • Scientific Description
    Supinoxin (RX-5902) is an orally active inhibitor of phosphorylated-p68 RNA helicase (P-p68) and a potent first-in-class anti-cancer agent. Supinoxin interacts with Y593 phosphorylated-p68 and attenuates the nuclear shuttling of beta-catenin. Supinoxin induces cell apoptosis and inhibits growth of TNBC cancer cell lines with IC50s ranging from 10 nM to 20 nM[1][2].
  • SMILES
    O=C(N1CCN(C2=CC(OC)=CC(OC)=C2)CC1)NC3=NC4=CC(F)=CC=C4N=C3OC
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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