Supinoxin

MedChem Express

Supinoxin [888478-45-3]

10

888478-45-3

Research Use Only

99.67

C22H24FN5O4

441.46

Supinoxin (RX-5902) is an orally active inhibitor of phosphorylated-p68 RNA helicase (P-p68) and a potent first-in-class anti-cancer agent . Supinoxin interacts with Y593 phosphorylated-p68 and attenuates the nuclear shuttling of beta-catenin. Supinoxin induces cell apoptosis and inhibits growth of TNBC cancer cell lines with IC 50 s ranging from 10 nM to 20 nM [1] [2] .

O=C(N1CCN(C2=CC(OC)=CC(OC)=C2)CC1)NC3=NC4=CC(F)=CC=C4N=C3OC

-20°C,2°C to 8°C

12352200