
IHC image of CSB-PA814232LA01HU diluted at 1:300 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
SUPV3L1 Antibody
CSB-PA814232LA01HU
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetSUPV3L1
Overview
- SupplierCusabio
- Product NameSUPV3L1 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID6832
- Target nameSUPV3L1
- Target descriptionSuv3 like RNA helicase
- Target synonymsSUV3, ATP-dependent RNA helicase SUPV3L1, mitochondrial, SUV3-like helicase, SUV3-like protein 1, suppressor of var1, 3-like 1, suppressor of var1, 3-like 1(SUV3)
- HostRabbit
- IsotypeIgG
- Protein IDQ8IYB8
- Protein NameATP-dependent RNA helicase SUPV3L1, mitochondrial
- Scientific DescriptionMajor helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3 overhang double-stranded RNA with a 3-to-5 directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5-to-3 direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161



