Surfen (dihydrochloride) [5424-37-3]
HY-122704A
CAS Number5424-37-3
Product group Chemicals
Estimated Purity99.0
Molecular Weight445.34
Overview
- SupplierMedChem Express
- Product NameSurfen (dihydrochloride) [5424-37-3]
- Delivery Days Customer10
- CAS Number5424-37-3
- CertificationResearch Use Only
- Estimated Purity99.0
- Molecular FormulaC21H22Cl2N6O
- Molecular Weight445.34
- Scientific DescriptionSurfen dihydrochloride is a potent heparan sulfate antagonist. Surfen inhibits FGF2 binding and signal transduction. Surfen binds to glycosaminoglycans and reduces tau hyperphosphorylation. Surfen dihydrochloride inhibits the activity of recombinant uronyl 2-O-sulfotransferase with an IC50 of approximately 2 microM. Surfen dihydrochloride inhibits HSV-1 viral infection. Surfen dihydrochloride inhibits neural differentiation, delays remyelination, and alleviates EAE[1][2][3][4][5][6].
- SMILESO=C(NC1=CC=C2N=C(C)C=C(N)C2=C1)NC3=CC=C4N=C(C)C=C(N)C4=C3.Cl.Cl
- Storage Instruction2°C to 8°C
- UNSPSC12352200
MSDS
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