Bio-Connect

Survivin-IN-1

HY-174336
MedChem Express
Molecular Weight820.04
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Survivin-IN-1
  • Delivery Days Customer
    999
  • Certification
    Research Use Only
  • Molecular Formula
    C47H66FN3O8
  • Molecular Weight
    820.04
  • Scientific Description
    Survivin-IN-1 (Compound II3) is a potent Survivin (a member of the Inhibitor of Apoptosis Protein family) inhibitor with an IC50 value of 8.1 microM against human lung cancer A549 cells and 9.0 microM against breast cancer MCF-7 cells. Survivin-IN-1 reduces Survivin protein levels and induces tumor cell apoptosis. Survivin-IN-1 is promising for research of malignant tumors such as lung cancer and breast cancer[1].
  • SMILES
    O=C(N1CCN(C(NC2=CC=C(F)C=C2)=O)CC1)[C@@]34CC[C@@]5(C)[C@]6(C)CCC7[C@@](COC(C)=O)(C)[C@@H](OC(C)=O)[C@H](OC(C)=O)C[C@]7(C)C6CC=C5C3[C@@H](C)[C@H](C)CC4
  • UNSPSC
    12352200