Swinholide A [95927-67-6]

AdipoGen Life Sciences

Swinholide A

10

95927-67-6

Research Use Only

>98%

Liquid

C78H132O20

1389.9

Cell permeable dimeric dilactone macrolide [1]. Cytotoxic compound [1, 2, 7]. Specific actin filament (F-actin) inhibitor. Disrupts the actin cytoskeleton by sequestering actin dimers and rapidly severing actin filaments (F-actin) [3, 5, 7, 8]. Depolymerizes actin filaments (F-actin) [6]. Antifungal [4]. Apoptosis inducer [9]. Alterates the actin cytoskeleton of GH4 cells and inhibits insulin-increased prolactin gene transcription [10]. - Chemical. CAS: 95927-67-6. Formula: C78H132O20. MW: 1389.9. Isolated from marine sponge Theonella swinhoei. Cell permeable dimeric dilactone macrolide. Cytotoxic compound. Specific actin filament (F-actin) inhibitor. Disrupts the actin cytoskeleton by sequestering actin dimers and rapidly severing actin filaments (F-actin). Depolymerizes actin filaments (F-actin). Antifungal. Apoptosis inducer. Alterates the actin cytoskeleton of GH4 cells and inhibits insulin-increased prolactin gene transcription.

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-20°C,2°C to 8°C

12352200