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Syk Inhibitor II (dihydrochloride dihydrate) [1965323-05-0]

HY-112390B
MedChem Express
CAS Number1965323-05-0
Product group Chemicals
Molecular Weight449.26
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Syk Inhibitor II (dihydrochloride dihydrate) [1965323-05-0]
  • Delivery Days Customer
    10
  • CAS Number
    1965323-05-0
  • Certification
    Research Use Only
  • Molecular Formula
    C14H21Cl2F3N6O3
  • Molecular Weight
    449.26
  • Scientific Description
    Syk Inhibitor II dihydrochloride dihydrate is a potent, high selective and ATP-competitive Syk inhibitor with an IC50 of 41 nM. Syk Inhibitor II dihydrochloride dihydrate inhibits 5-HT release from RBL-cells with an IC50 of 460 nM. Syk Inhibitor II dihydrochloride dihydrate shows less potent against other kinases and has anti-allergic effect[1].
  • SMILES
    O=C(C1=CN=C(NCCN)N=C1NC2=CC=CC(C(F)(F)F)=C2)N.[H]Cl.[H]Cl.O.O
  • UNSPSC
    12352200