SYNE4 Antibody

Cusabio

SYNE4 Antibody

20

ELISA

Research Use Only

Polyclonal

Unconjugated

SYNE4

spectrin repeat containing nuclear envelope family member 4

C19orf46, DFNB76, KASH4, Nesp4, nesprin-4, KASH domain-containing protein 4, deafness, autosomal recessive 76, nuclear envelope spectrin repeat protein 4

Rabbit

IgG

Nesprin-4

As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Behaves as a kinesin cargo, providing a functional binding site for kinesin-1 at the nuclear envelope. Hence may contribute to the establishment of secretory epithelial morphology by promoting kinesin-dependent apical migration of the centrosome and Golgi apparatus and basal localization of the nucleus.

Human

-20°C or -80°C

41116161