Various tissue extracts (50 microg) were separated by 5% SDS-PAGE, and the membrane was blotted with SYNGAP1 antibody (GTX131673) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
Various tissue extracts (50 microg) were separated by 5% SDS-PAGE, and the membrane was blotted with SYNGAP1 antibody (GTX131673) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
SYNGAP1 antibody
GTX131673
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameSYNGAP1 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1.38 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a Ras GTPase activating protein that is a member of the N-methyl-D-aspartate receptor complex. The N-terminal domain of the protein contains a Ras-GAP domain, a pleckstrin homology domain, and a C2 domain that may be involved in binding of calcium and phospholipids. The C-terminal domain consists of a ten histidine repeat region, serine and tyrosine phosphorylation sites, and a T/SXV motif required for postsynaptic scaffold protein interaction. The encoded protein negatively regulates Ras, Rap and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor trafficking to the postsynaptic membrane to regulate synaptic plasticity and neuronal homeostasis. Allelic variants of this gene are associated with intellectual disability and autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203