(-)-Syringaresinol [6216-81-5]

MedChem Express

(-)-Syringaresinol [6216-81-5]

10

6216-81-5

Research Use Only

99.95

C22H26O8

418.44

(-)-Syringaresinol is an orally active isomer of syringaresinol (HY-N8307) found in Annona Montana. (-)-Syringaresinol exhibits antioxidant, anti-inflammatory, and anticancer activities. (-)-Syringaresinol can alleviate ulcerative colitis via the PI3K-Akt/MAPK/Wnt signaling pathway. (-)-Syringaresinol inhibits HL-60 cell proliferation by arresting the G1 phase and inducing apoptosis. (-)-Syringaresinol inhibits LPS (HY-D1056)-induced microglial activation by downregulating the NF-kappaB p65 signaling pathway and its interaction with ERbeta, exerting anti-neuroinflammatory effects[1][2][3].

OC1=C(OC)C=C([C@@H]2OC[C@]3([H])[C@@]2([H])CO[C@H]3C4=CC(OC)=C(O)C(OC)=C4)C=C1OC

2°C to 8°C

12352200