T-1840383 [1195779-24-8]

MedChem Express

T-1840383 [1195779-24-8]

5

1195779-24-8

Research Use Only

C30H25ClFN5O4

574.00

T-1840383 is a potent, ATP-competitive inhibitor of c-Met/VEGFR-2, with the IC50s of 1.9 nM, 7.7 nM, 2.2 nM and 5.5 nM for c-Met, VEGFR1, VEGFR2 and VEGFR3, respectively[1].

O=C(NC1=CC=C(C(F)=C1)OC2=CN3C(C=C2)=NC(NC(C4CC4)=O)=C3)C5=CC=C(N(C5=O)C6=CC=CC=C6)C.Cl

12352200