T-Type calcium channel inhibitor 2

MedChem Express

T-Type calcium channel inhibitor 2 [2771965-57-0]

10

Research Use Only

C36H39FN4OS

594.78

T-Type calcium channel inhibitor 2 (compound 6g) is a potent T-type calcium channel inhibitor with IC50s of 31.0, 83.1, 69.3 microM for Cav3.1 (alpha1G), Cav3.2 (alpha1H), Cav3.3 (alpha1I) (alpha1H), respectively. T-Type calcium channel inhibitor 2 shows cytotoxicity for A549, HCT-116 cells with IC50s of 5.0, 6.4 microM, respectively[1].

CN(CCCCCSC1=NC2=CC=CC=C2C(N1C3=CC=C(C=C3)C4=CC=CC=C4)CC(NCC5=CC=C(C=C5)F)=O)C

12131703