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T2AA [1380782-27-3]

T2AA [1380782-27-3]

T35719
TargetMol Chemicals
CAS Number1380782-27-3
Product group Chemicals
Estimated Purity98.19%
Molecular Weight511.09
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    T2AA [1380782-27-3]
  • Delivery Days Customer
    4
  • CAS Number
    1380782-27-3
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    T2AA
  • Estimated Purity
    98.19%
  • Molecular Formula
    C15H15I2NO3
  • Molecular Weight
    511.09
  • Scientific Description
    T2AA (4-[4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy]phenol) is an inhibitor of proliferating cell nuclear antigen (PCNA) with IC50 of 1 microM for PCNA/PIP-box peptide interaction. T2AA suppresses cancer cell growth and causes DNA replication stress by stalling DNA replication forks and inhibiting PCNA interaction with DNA polymerase delta.
  • Shelf life instruction
    3 years
  • SMILES
    N[C@H](CO)Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200