T4 RNA Ligase II (TRL-BE103)

KACTUS

T4 RNA Ligase II (TRL-BE103)

9

Liquid

T4 RNA Ligase II, also known as T4 Rnl2 (gp24.1), is an ATP-dependent RNA ligase catalyzing the inter- and intramolecular RNA strand joining activity via phosphodiester bond formation. Unlike T4 RNA Ligase I, T4 RNA Ligase II is much more active in joining nicks on double-stranded RNA (dsRNA) than joining the ends of single-stranded RNA. The enzyme can also ligate the 3 OH of RNA to the 5 phosphate of DNA in a double-stranded structure. The enzyme requires an adjacent 5 phosphate and 3 OH for ligation.

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