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T6167923

HY-19744
MedChem Express
CAS Number2437475-16-4
DownloadMSDS
Product group Chemicals
Estimated Purity99.40
Molecular Weight458.39
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Overview

  • Supplier
    MedChem Express
  • Product Name
    T6167923 [2437475-16-4]
  • Delivery Days Customer
    10
  • CAS Number
    2437475-16-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.40
  • Molecular Formula
    C17H20BrN3O3S2
  • Molecular Weight
    458.39
  • Scientific Description
    T6167923 is a selective inhibitor of MyD88-dependent signaling pathways. T6167923 directly binds to Toll/IL1 receptor (TIR) domain of MyD88 and disrupts MyD88 homodimeric formation. T6167923 inhibits NF-kappaB driven Staphylococcus enterotoxin AP (SEAP) activity, and improves anti-inflammatory activity with IC 50 s of 2.7 ?microM, 2.9 microM, 2.66 microM and 2.66 microM for IFN-gamma, IL-1beta, IL-6 and TNF-alpha, respectively [1] [2] .
  • SMILES
    BrC1=CC(S(=O)(N2CCN(C(N[C@H](C3=CC=CS3)C)=O)CC2)=O)=CC=C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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