Bio-Connect

TAB3 blocking peptide

Research Use Only
GTX31693-PEP
GeneTex
ApplicationsNeutralisation/Blocking
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    GeneTex
  • Product Name
    TAB3 blocking peptide
  • Delivery Days Customer
    9
  • Applications
    Neutralisation/Blocking
  • Certification
    Research Use Only
  • Concentration
    200 ug/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Scientific Description
    The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
  • Storage Instruction
    -20°C
  • UNSPSC
    12352202