
Western Blot Positive WB detected in: K562 whole cell lysate, THP-1 whole cell lysate All lanes: TACC3 Antibody at 1:1000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 91 kDa Observed band size: 140 kDa
TACC3 Recombinant Monoclonal Antibody
CSB-RA553945A0HU
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetTACC3
Overview
- SupplierCusabio
- Product NameTACC3 Recombinant Monoclonal Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID10G7
- ConjugateUnconjugated
- Gene ID10460
- Target nameTACC3
- Target descriptiontransforming acidic coiled-coil containing protein 3
- Target synonymsERIC1; ERIC-1; maskin; Tacc4; transforming acidic coiled-coil-containing protein 3
- IsotypeIgG
- Protein IDQ9Y6A5
- Protein NameTransforming acidic coiled-coil-containing protein 3
- Scientific DescriptionPlays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:21297582, PubMed:23532825). May be involved in the control of cell growth and differentiation. May contribute to cancer (PubMed:14767476).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203