Tafamidis

MedChem Express

Tafamidis [594839-88-0]

10

594839-88-0

Research Use Only

99.89

C14H7Cl2NO3

308.12

Tafamidis is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC 50 s of 2.7-3.2 microM. Tafamidis inhibits amyloidogenesis [1] .

O=C(C1=CC=C2N=C(C3=CC(Cl)=CC(Cl)=C3)OC2=C1)O

-20°C,2°C to 8°C

12352200