Tafamidis-d3

MedChem Express

Tafamidis-d3

10

Research Use Only

C14H4D3Cl2NO3

311.13

Tafamidis-d3 is deuterium labeled Tafamidis. Tafamidis is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 microM. Tafamidis inhibits amyloidogenesis[1].

O=C(C1=C([2H])C([2H])=C2N=C(C3=CC(Cl)=CC(Cl)=C3)OC2=C1[2H])O

12131703