Tafamidis meglumine [951395-08-7]

MedChem Express

Tafamidis meglumine [951395-08-7]

10

951395-08-7

Research Use Only

99.79

C21H24Cl2N2O8

503.33

Tafamidis meglumine (Fx-1006A) is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 microM. Tafamidis meglumine inhibits amyloidogenesis[1].

O=C(C1=CC=C2N=C(C3=CC(Cl)=CC(Cl)=C3)OC2=C1)O.O[C@@H]([C@@H]([C@@H](CO)O)O)[C@@H](O)CNC

2°C to 8°C

12131703