TAK-285 [871026-44-7]
HY-15196
CAS Number871026-44-7
Product group Chemicals
Estimated Purity99.70
Molecular Weight547.96
Overview
- SupplierMedChem Express
- Product NameTAK-285 [871026-44-7]
- Delivery Days Customer10
- CAS Number871026-44-7
- CertificationResearch Use Only
- Estimated Purity99.70
- Molecular FormulaC26H25ClF3N5O3
- Molecular Weight547.96
- Scientific DescriptionTAK-285 is a potent, selective, ATP-competitive and orally active HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, respectively. TAK-285 is >10-fold selectivity for HER1/2 than HER4, and less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. TAK-285 has effective antitumor activity[1]. TAK-285 can cross the blood-brain barrier (BBB)[2].
- SMILESClC(C=C(NC1=NC=NC2=C1N(CCNC(CC(C)(C)O)=O)C=C2)C=C3)=C3OC4=CC=CC(C(F)(F)F)=C4
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
MSDS
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