TAK-715

MedChem Express

TAK-715 [303162-79-0]

10

303162-79-0

Research Use Only

99.76

C24H21N3OS

399.51

TAK-715 is an orally active and potent p38 MAPK inhibitor with IC 50 s of 7.1 nM, 200 nM for p38alpha and p38beta, respectively. TAK-715 inhibits casein kinase I (CK1delta/epsilon) to regulate activation of Wnt/beta-catenin signaling. TAK-715 shows good significant efficacy in a rat arthritis model [1] [2] .

O=C(C1=CC=CC=C1)NC2=NC=CC(C3=C(N=C(S3)CC)C4=CC=CC(C)=C4)=C2

-20°C,2°C to 8°C

12352200