TAK-733

Biorbyt

TAK-733

16

1035555-63-5

Research Use Only

C17H15F2IN4O4

504.23

TAK-733 is a potent and selective MEK allosteric site inhibitor for MEK1 with IC50 of 3.2 nM, inactive to Abl1, AKT3, c-RAF, CamK1, CDK2, c-Met, etc.

C1N(C[C@H](O)CO)C(=O)C2C(NC3=CC=C(I)C=C3F)=C(F)C(=O)N(C)C=2N=1

12352200