TAK-779

MedChem Express

TAK-779 [229005-80-5]

10

229005-80-5

Research Use Only

99.73

C33H39ClN2O2

531.13

TAK-779 is a potent and selective nonpeptide antagonist of CCR5 and CXCR3 , with a K i of 1.1 nM for CCR5, and effectively and selectively inhibits R5 HIV-1 , with EC 50 and EC 90 of 1.2 nM and 5.7 nM, respectively, in MAGI-CCR5 cells.

C[N+](C)(CC1=CC=C(NC(C2=CC3=CC(C4=CC=C(C)C=C4)=CC=C3CCC2)=O)C=C1)C5CCOCC5.[Cl-]

-20°C

12352200