Takinib

AbMole BioScience

Takinib

9

1111556-37-6

Chemical

Research Use Only

C18H18N4O2

322.36

Takinib is a potent and selective TAK1 inhibitor with an IC50 of 9.5 nM, more than 1.5 log more potent than the second and third ranked targets, IRAK4 (120 nM) and IRAK1 (390 nM), respectively.

CCC[N]1C(=NC2=CC=CC=C12)NC(=O)C3=CC(=CC=C3)C(N)=O

12352200