Talabostat (mesylate)

MedChem Express

Talabostat (mesylate) [150080-09-4]

10

150080-09-4

98.35

C10H23BN2O6S

310.18

Talabostat mesylate (Val-boroPro mesylate; PT100 mesylate) is an orally active and nonselective dipeptidyl peptidase IV (DPP-IV) inhibitor ( IC 50 K i = 0.18 nM) and the inhibitor of fibroblast activation protein (FAP) ( IC 50 = 560 nM), inhibits DPP8/9 ( IC 50 = 4/11 nM; K i = 1.5/0.76 nM), quiescent cell proline dipeptidase (QPP) ( IC 50 = 310 nM), DPP2, and some other DASH family enzymes. Antineoplastic and hematopoiesis- stimulating activities [1] [2] [3] .

CC(C)[C@H](N)C(N1[C@H](B(O)O)CCC1)=O.CS(=O)(O)=O

2°C to 8°C

12352200