Bio-Connect

Taletrectinib [1505515-69-4]

HY-131003
MedChem Express
CAS Number1505515-69-4
Product group Chemicals
Estimated Purity99.78
Molecular Weight551.61
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Taletrectinib [1505515-69-4]
  • Delivery Days Customer
    9
  • CAS Number
    1505515-69-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.78
  • Molecular Formula
    C29H34FN5O5
  • Molecular Weight
    551.61
  • Scientific Description
    Taletrectinib (DS-6051b) is a potent, orally active, and next-generation selective ROS1/NTRK inhibitor. Taletrectinib potently inhibits recombinant ROS1, NTRK1, NTRK2, and NTRK3 with IC50s of 0.207, 0.622, 2.28, and 0.98 nM, respectively. Taletrectinib also inhibits ROS1 G2032R and other Crizotinib-resistant ROS1 mutants[1][2].
  • SMILES
    O=C(O)CCCCC(O)=O.C[C@@H](NC1=NN2C(C=C1)=NC=C2C3=CC=C(OC[C@H](N)C)C=C3)C4=CC=CC(F)=C4
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200