Taletrectinib [1505515-69-4]
HY-131003
CAS Number1505515-69-4
Product group Chemicals
Estimated Purity99.78
Molecular Weight551.61
Overview
- SupplierMedChem Express
- Product NameTaletrectinib [1505515-69-4]
- Delivery Days Customer9
- CAS Number1505515-69-4
- CertificationResearch Use Only
- Estimated Purity99.78
- Molecular FormulaC29H34FN5O5
- Molecular Weight551.61
- Scientific DescriptionTaletrectinib (DS-6051b) is a potent, orally active, and next-generation selective ROS1/NTRK inhibitor. Taletrectinib potently inhibits recombinant ROS1, NTRK1, NTRK2, and NTRK3 with IC50s of 0.207, 0.622, 2.28, and 0.98 nM, respectively. Taletrectinib also inhibits ROS1 G2032R and other Crizotinib-resistant ROS1 mutants[1][2].
- SMILESO=C(O)CCCCC(O)=O.C[C@@H](NC1=NN2C(C=C1)=NC=C2C3=CC=C(OC[C@H](N)C)C=C3)C4=CC=CC(F)=C4
- Storage Instruction2°C to 8°C
- UNSPSC12352200
![Taletrectinib [1505515-69-4]](https://www.targetmol.com/group3/M00/03/89/CgoaEWY7TwyEVSKNAAAAADjostM675.png)