Talotrexin (ammonium)

MedChem Express

Talotrexin (ammonium) [678991-55-4]

10

678991-55-4

Research Use Only

C27H27N9O6.xH3N

Talotrexin ammonium is a nonpolyglutamatable antifolate. Talotrexin ammonium improves antitumor activity in a broad spectrum of cancer models by targeting DHFR to inhibit tumor growth [1] .

NC1=NC(N)=NC2=C1N=C(CNC3=CC=C(C=C3)C(N[C@H](C(O)=O)CCCNC(C4=C(C=CC=C4)C(O)=O)=O)=O)C=N2.N.[x]

12352200