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TAME hydrochloride --- Ubiquitin Ligase APC/C Inhibitor

BS-60246C
Bioss
Estimated Purity98.0
Product group Chemicals
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Overview

  • Supplier
    Bioss
  • Product Name
    TAME hydrochloride --- Ubiquitin Ligase APC/C Inhibitor
  • Delivery Days Customer
    16
  • Certification
    Research Use Only
  • Estimated Purity
    98.0
  • Scientific Description
    TAME is a competitive inhibitor of the ubiquitin ligase anaphase-promoting complex/cyclosome (APC/C). It promotes Cdc20 autoubiquitination and inhibits cyclin proteolysis in mitotic Xenopus oocyte extracts (IC50 ~ 12 microM) and blocks cyclin degradation in interphase extract.
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000