Tandutinib

MedChem Express

Tandutinib [387867-13-2]

10

387867-13-2

Research Use Only

99.48

C31H42N6O4

562.70

Tandutinib (MLN518) is a potent and selective inhibitor of the FLT3 with an IC 50 of 0.22 microM, and also inhibits c-Kit and PDGFR with IC 50 s of 0.17 microM and 0.20 microM, respectively. Tandutinib can be used for acute myelogenous leukemia (AML) [1] [2] . Tandutinib has the ability to cross the blood-brain barrier [3] .

O=C(N1CCN(C2=C(C(C=C3OCCCN4CCCCC4)=NC=N2)C=C3OC)CC1)NC5=CC=C(OC(C)C)C=C5

-20°C,2°C to 8°C

12352200