Tanespimycin

MedChem Express

Tanespimycin [75747-14-7]

10

75747-14-7

Research Use Only

99.01

C31H43N3O8

585.69

Tanespimycin (17-AAG) is a potent HSP90 inhibitor with an IC 50 of 5 nM, having a 100-fold higher binding affinity for tumour cell derived HSP90 than normal cell derived HSP90 [1] [5] . Tanespimycin depletes cellular STK38/NDR1 and reduces STK38 kinase activity. Tanespimycin also downregulates the stk38 gene expression [3] .

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2°C to 8°C

12352200