TAO Kinase inhibitor 1 [850467-66-2]
T16987
CAS Number850467-66-2
Product group Chemicals
Estimated Purity99.45%
Molecular Weight384.47
Overview
- SupplierTargetMol Chemicals
- Product NameTAO Kinase inhibitor 1 [850467-66-2]
- Delivery Days Customer4
- CAS Number850467-66-2
- CertificationResearch Use Only
- Chemical NameTAO Kinase inhibitor 1
- Estimated Purity99.45%
- Molecular FormulaC25H24N2O2
- Molecular Weight384.47
- Scientific DescriptionTAO Kinase inhibitor 1 delays mitosis and induces mitotic cell death. TAO Kinase inhibitor 1 is a selective and ATP-competitive thousand-and-one amino acid kinases inhibitor (IC50s: 11 to 15 nM for TAOK1 and 2, respectively).
- Shelf life instruction3 years
- SMILESN(C(CNC(=O)C1=CC=C(C=C1)C2=CC=CC=C2)=O)C3C=4C(CCC3)=CC=CC4
- Storage Instruction-20°C
- UNSPSC51202000
References
- Koo CY, Giacomini C, Reyes-Corral M, et al. Targeting TAO Kinases Using a New Inhibitor Compound Delays Mitosis and Induces Mitotic Cell Death in Centrosome Amplified Breast Cancer Cells. Mol Cancer Ther. 2017,16(11):2410-2421. doi: 10.1158/1535-7163.MCT-17-0077Read this paper
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